Research records indexed for Humanin
This page carries 12 of the 587 records that the literature query returned for Humanin, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 575 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is Humanin.
Indexed records
| Record | Year | Study type | Model | n as stated | What it reported |
|---|---|---|---|---|---|
| Protective Mechanism of Humanin Against Oxidative Stress in Aging-Related Cardiovascular Diseases pmid:34177809 | 2021 | review-article, Review | other | Not stated | Indexed as review-article, review. study model from MeSH "Animals" with no rodent species heading. subject headings: Cardiovascular Diseases; Protein Kinases; Intracellular Signaling Peptides And Proteins; Oxidative Stress; Aging. |
| Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging pmid:33131010 | 2021 | Research Support, Non-U.S. Gov't, research-article | other | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Humans" with no interventional publication type. subject headings: Alzheimer Disease; Diabetes Mellitus, Type 2; Fibroblast Growth Factors; Intracellular Signaling Peptides And Proteins; Aged, 80 And Over. |
| Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases pmid:33130077 | 2021 | Review | other | Not stated | Indexed as review. study model from MeSH "Animals" with no rodent species heading. subject headings: Mitochondria; Neoplasms; Neurodegenerative Diseases; Diabetes Mellitus; Intracellular Signaling Peptides And Proteins. |
| Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway pmid:33337472 | 2021 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Ovary; Granulosa Cells; Cell Line, Tumor; Rats, Sprague-Dawley; Polycystic Ovary Syndrome. |
| The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan pmid:32575074 | 2020 | Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, n.i.h., intramural, research support, non-u.s. gov't. study model from MeSH "Mice". subject headings: Mitochondria; Animals, Genetically Modified; Macaca Mulatta; Mole Rats; Caenorhabditis Elegans. |
| The Mitochondria-Derived Peptide Humanin Improves Recovery from Intracerebral Hemorrhage: Implication of Mitochondria Transfer and Microglia Phenotype Change pmid:31980585 | 2020 | research-article, Research Support, N.I.H., Extramural | rodent | Not stated | Indexed as research-article, research support, n.i.h., extramural. study model from MeSH "Mice, Inbred C57bl". subject headings: Astrocytes; Microglia; Mitochondria; Mice, Inbred C57BL; Rats, Sprague-Dawley. |
| Reduced skeletal muscle expression of mitochondrial-derived peptides humanin and MOTS-C and Nrf2 in chronic kidney disease pmid:31432706 | 2019 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Muscle, Skeletal; Mitochondria, Muscle; Intracellular Signaling Peptides And Proteins; Mitochondrial Proteins; Gene Expression Regulation. |
| Humanin is an endogenous activator of chaperone-mediated autophagy pmid:29187525 | 2018 | Research Support, Non-U.S. Gov't, research-article | rodent | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Mice". subject headings: Cells, Cultured; NIH 3T3 Cells; Lysosomes; Cytosol; Rats, Wistar. |
| Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans pmid:30242290 | 2018 | research-article, Research Support, U.S. Gov't, Non-P.H.S. | rodent | Not stated | Indexed as research-article, research support, u.s. gov't, non-p.h.s.. study model from MeSH "Mice, Inbred C57bl". subject headings: Cell Line, Tumor; Mitochondria; Mice, Inbred C57BL; Neurodegenerative Diseases; Peptides. |
| Chronic treatment with the mitochondrial peptide humanin prevents age-related myocardial fibrosis in mice pmid:30004252 | 2018 | Research Support, Non-U.S. Gov't, research-article | rodent | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Mice, Inbred C57bl". subject headings: Cell Line, Tumor; Fibroblasts; Myocytes, Cardiac; Mice, Inbred C57BL; Cardiomyopathies. |
| Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage pmid:28726777 | 2017 | Clinical Trial, Research Support, Non-U.S. Gov't | human trial | Not stated | Indexed as clinical trial, research support, non-u.s. gov't. study model from MeSH "Humans" with publication type "clinical trial". subject headings: Mitochondria; Macular Degeneration; Intracellular Signaling Peptides And Proteins; Mitochondrial Proteins; Cell Survival. |
| Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells pmid:28814984 | 2017 | review-article, Review | other | Not stated | Indexed as review-article, review. study model from MeSH "Humans" with no interventional publication type. subject headings: Mitochondria; Macular Degeneration; Reactive Oxygen Species; Intracellular Signaling Peptides And Proteins; Signal Transduction. |
Where this page sits
Compound page: Humanin. Class: Mitochondrial and longevity-associated peptides.
Retrieved 2026-10-10.
Sources
- PubChem Compound Summary for CID 16131438, Humanin. PubChem, National Library of Medicine (2026). pubchem:16131438
- Drugs@FDA application register query for this compound, no application records returned. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:humanin
- Humanin: a harbinger of mitochondrial-derived peptides?. Trends in endocrinology and metabolism: TEM (2013). pmid:23402768
- Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature (2003). pmid:12732850
- Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein. Biochemical and biophysical research communications (2001). pmid:11327724
- Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis. Proceedings of the National Academy of Sciences of the United States of America (2003). pmid:14561895
- Humanin: a novel central regulator of peripheral insulin action. PloS one (2009). pmid:19623253
- The emerging role of the mitochondrial-derived peptide humanin in stress resistance. Journal of molecular endocrinology (2013). pmid:23239898
On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.