Research records indexed for Mechano growth factor
This page carries 12 of the 222 records that the literature query returned for Mechano growth factor, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 210 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is Mechano growth factor.
Indexed records
| Record | Year | Study type | Model | n as stated | What it reported |
|---|---|---|---|---|---|
| The role of mechano growth factor in chondrocytes and cartilage defects: a concise review pmid:37171185 | 2023 | research-article, Review | other | Not stated | Indexed as research-article, review. study model from MeSH "Humans" with no interventional publication type. subject headings: Cartilage; Cartilage, Articular; Chondrocytes; Osteoarthritis; Insulin-Like Growth Factor I. |
| Improved Muscle Regeneration into a Joint Prosthesis with Mechano-Growth Factor Loaded within Mesoporous Silica Combined with Carbon Nanotubes on a Porous Titanium Alloy pmid:36053268 | 2022 | Research Support, Non-U.S. Gov't | other | Not stated | Indexed as research support, non-u.s. gov't. study model from assigned MeSH headings do not state a study model. subject headings: Muscles; Nanotubes, Carbon; Titanium; Alloys; Silicon Dioxide. |
| Mechano-growth factor protects against mechanical overload induced damage and promotes migration of growth plate chondrocytes through RhoA/YAP pathway pmid:29470961 | 2018 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Growth Plate; Cells, Cultured; Chondrocytes; Rats, Sprague-Dawley; Inflammation. |
| Increased nuclear stiffness via FAK-ERK1/2 signaling is necessary for synthetic mechano-growth factor E peptide-induced tenocyte migration pmid:26742689 | 2016 | Research Support, Non-U.S. Gov't, research-article | rodent | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Rats". subject headings: Cell Nucleus; Chromatin; Rats, Sprague-Dawley; Sulfones; Flavonoids. |
| In vitro and in vivo degradation and mechanical properties of ZEK100 magnesium alloy coated with alginate, chitosan and mechano-growth factor pmid:27040239 | 2016 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Femur; Rats, Wistar; Magnesium; Alloys; Glucuronic Acid. |
| Mechano growth factor (MGF) and transforming growth factor (TGF)-β3 functionalized silk scaffolds enhance articular hyaline cartilage regeneration in rabbit model pmid:25818452 | 2015 | Research Support, Non-U.S. Gov't | other | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Animals" with no rodent species heading. subject headings: Cartilage, Articular; Stem Cells; Mesenchymal Stem Cells; Rabbits; Fibrosis. |
| Mechano-growth factor accelerates the proliferation and osteogenic differentiation of rabbit mesenchymal stem cells through the PI3K/AKT pathway pmid:25588515 | 2015 | research-article | other | Not stated | Indexed as research-article. study model from MeSH "Animals" with no rodent species heading. subject headings: Osteoblasts; Mesenchymal Stem Cells; Rabbits; Insulin-Like Growth Factor I; Signal Transduction. |
| Localized delivery of mechano-growth factor E-domain peptide via polymeric microstructures improves cardiac function following myocardial infarction pmid:25678113 | 2015 | research-article, Research Support, N.I.H., Extramural | rodent | Not stated | Indexed as research-article, research support, n.i.h., extramural. study model from MeSH "Mice, Inbred C57bl". subject headings: Mice, Inbred C57BL; Myocardial Infarction; Polymers; Peptides; Insulin-Like Growth Factor I. |
| Increased IGF-IEc expression and mechano-growth factor production in intestinal muscle of fibrostenotic Crohn's disease and smooth muscle hypertrophy pmid:26428636 | 2015 | research-article, Research Support, N.I.H., Extramural | other | Not stated | Indexed as research-article, research support, n.i.h., extramural. study model from MeSH "Humans" with no interventional publication type. subject headings: Muscle, Smooth; Intestines; Intestinal Mucosa; Cells, Cultured; Myocytes, Smooth Muscle. |
| Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells pmid:24253050 | 2014 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Mice". subject headings: Cells, Cultured; Myoblasts; Stem Cells; Insulin-Like Growth Factor I; Peptide Fragments. |
| Mechano growth factor E peptide regulates migration and differentiation of bone marrow mesenchymal stem cells pmid:24323763 | 2014 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Bone Marrow Cells; Adipocytes; Osteoblasts; Mesenchymal Stem Cells; Rats, Sprague-Dawley. |
| A synthetic mechano-growth factor E peptide promotes rat tenocyte migration by lessening cell stiffness and increasing F-actin formation via the FAK-ERK1/2 signaling pathway pmid:24434354 | 2014 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Achilles Tendon; Cells, Cultured; Rats, Sprague-Dawley; Actins; Insulin-Like Growth Factor I. |
Where this page sits
Compound page: Mechano growth factor. Class: Growth factors and growth hormone-derived compounds.
Retrieved 2026-10-12.
Sources
- Drugs@FDA application register query for this compound, no application records returned. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:mgf
- Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration. Endocrinology (2010). pmid:20130113
- Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages. Mechanisms of ageing and development (2011). pmid:21354439
- A new pro-migratory activity on human myogenic precursor cells for a synthetic peptide within the E domain of the mechano growth factor. Experimental cell research (2007). pmid:17156777
- Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction. Heart, lung & circulation (2008). pmid:17581790
- Mechano-growth factor, an IGF-I splice variant, rescues motoneurons and improves muscle function in SOD1(G93A) mice. Experimental neurology (2009). pmid:19038252
- Mechano growth factor E peptide promotes osteoblasts proliferation and bone-defect healing in rabbits. International orthopaedics (2011). pmid:21057789
- Mechano growth factor (MGF) and transforming growth factor (TGF)-β3 functionalized silk scaffolds enhance articular hyaline cartilage regeneration in rabbit model. Biomaterials (2015). pmid:25818452
- Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells. American journal of physiology. Endocrinology and metabolism (2014). pmid:24253050
On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.