Research records indexed for Leuprolide

This page carries 12 of the 2,436 records that the literature query returned for Leuprolide, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 2,424 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is Leuprolide.

Indexed records

Records retrieved for Leuprolide, newest first
RecordYearStudy typeModeln as statedWhat it reported
Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Prostate Cancer: The Primary Results of the PRONOUNCE Randomized Trial pmid:344592142021Research Support, Non-U.S. Gov't, research-articlehuman trialNot statedIndexed as research support, non-u.s. gov't, research-article. study model from MeSH "Humans" with publication type "randomized controlled trial". subject headings: Prostatic Neoplasms; Leuprolide; Oligopeptides; Prospective Studies.
Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone pmid:308112822019Clinical Trial, Phase II, Comparative Studyhuman trialNot statedIndexed as clinical trial, phase ii, comparative study. study model from MeSH "Humans" with publication type "clinical trial, phase ii". subject headings: Adenocarcinoma; Prostatic Neoplasms; Neoplasm, Residual; Benzamides; Nitriles.
Intense androgen-deprivation therapy with abiraterone acetate plus leuprolide acetate in patients with localized high-risk prostate cancer: results of a randomized phase II neoadjuvant study pmid:253112172014Clinical Trial, Phase II, Research Support, N.I.H., Intramuralhuman trialNot statedIndexed as clinical trial, phase ii, research support, n.i.h., intramural. study model from MeSH "Humans" with publication type "clinical trial, phase ii". subject headings: Prostatic Neoplasms; Androstadienes; Testosterone; Androgen Antagonists; Leuprolide.
Ulipristal acetate versus leuprolide acetate for uterine fibroids pmid:222960762012Clinical Trial, Phase III, Comparative Studyhuman trialNot statedIndexed as clinical trial, phase iii, comparative study. study model from MeSH "Humans" with publication type "clinical trial, phase iii". subject headings: Endometrium; Leiomyoma; Uterine Neoplasms; Menorrhagia; Norpregnadienes.
Comparison of "triggers" using leuprolide acetate alone or in combination with low-dose human chorionic gonadotropin pmid:215500422011Comparative StudyotherNot statedIndexed as comparative study. study model from MeSH "Humans" with no interventional publication type. subject headings: Ovarian Hyperstimulation Syndrome; Chorionic Gonadotropin; Leuprolide; Fertility Agents, Female; Drug Therapy, Combination.
A phase III extension trial with a 1-arm crossover from leuprolide to degarelix: comparison of gonadotropin-releasing hormone agonist and antagonist effect on prostate cancer pmid:217880332011Clinical Trial, Phase III, Comparative Studyhuman trialNot statedIndexed as clinical trial, phase iii, comparative study. study model from MeSH "Humans" with publication type "clinical trial, phase iii". subject headings: Prostatic Neoplasms; Leuprolide; Oligopeptides; Antineoplastic Agents, Hormonal; Cross-Over Studies.
Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial pmid:200895222010Research Support, Non-U.S. Gov't, Multicenter Studyhuman trialNot statedIndexed as research support, non-u.s. gov't, multicenter study. study model from MeSH "Humans" with publication type "randomized controlled trial". subject headings: Endometriosis; Pelvic Pain; Nandrolone; Leuprolide; Progestins.
Additional analysis of the secondary end point of biochemical recurrence rate in a phase 3 trial (CS21) comparing degarelix 80 mg versus leuprolide in prostate cancer patients segmented by baseline characteristics pmid:199622272010Clinical Trial, Phase III, Comparative Studyhuman trialNot statedIndexed as clinical trial, phase iii, comparative study. study model from MeSH "Humans" with publication type "clinical trial, phase iii". subject headings: Prostatic Neoplasms; Neoplasm Recurrence, Local; Leuprolide; Prostate-Specific Antigen; Oligopeptides.
Leuprolide acetate: a drug of diverse clinical applications pmid:179706432007Research Support, Non-U.S. Gov't, ReviewotherNot statedIndexed as research support, non-u.s. gov't, review. study model from MeSH "Animals" with no rodent species heading. subject headings: Leiomyoma; Prostatic Neoplasms; Endometriosis; Puberty, Precocious; Leuprolide.
Subcutaneous depot medroxyprogesterone acetate versus leuprolide acetate in the treatment of endometriosis-associated pain pmid:161769392006Comparative Study, Multicenter Studyhuman trialNot statedIndexed as comparative study, multicenter study. study model from MeSH "Humans" with publication type "randomized controlled trial". subject headings: Hip; Lumbar Vertebrae; Endometriosis; Uterine Diseases; Pelvic Pain.
Subcutaneous injection of depot medroxyprogesterone acetate compared with leuprolide acetate in the treatment of endometriosis-associated pain pmid:165952062006Clinical Trial, Phase III, Research Support, Non-U.S. Gov'thuman trialNot statedIndexed as clinical trial, phase iii, research support, non-u.s. gov't. study model from MeSH "Humans" with publication type "clinical trial, phase iii". subject headings: Pain; Endometriosis; Uterine Hemorrhage; Flushing; Leuprolide.
Bicalutamide monotherapy versus leuprolide monotherapy for prostate cancer: effects on bone mineral density and body composition pmid:152263232004Clinical Trial, Research Support, U.S. Gov't, P.H.S.human trialNot statedIndexed as clinical trial, research support, u.s. gov't, p.h.s.. study model from MeSH "Humans" with publication type "clinical trial". subject headings: Prostatic Neoplasms; Anilides; Tosyl Compounds; Nitriles; Leuprolide.

Where this page sits

Compound page: Leuprolide. Class: Endocrine and immune signalling peptides.

Retrieved 2026-10-12.

Sources

  1. PubChem Compound Summary for CID 657181, Leuprolide. PubChem, National Library of Medicine (2026). pubchem:657181
  2. Drugs@FDA application register query for this compound, 21 application(s) returned: ANDA215336, NDA211488, NDA020011, ANDA217437, NDA021488. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:leuprolide
  3. Leuprolide versus diethylstilbestrol for metastatic prostate cancer. The New England journal of medicine (1984). pmid:6436700
  4. A controlled trial of leuprolide with and without flutamide in prostatic carcinoma. The New England journal of medicine (1989). pmid:2503724
  5. Intense androgen-deprivation therapy with abiraterone acetate plus leuprolide acetate in patients with localized high-risk prostate cancer: results of a randomized phase II neoadjuvant study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2014). pmid:25311217
  6. Lupron depot (leuprolide acetate for depot suspension) in the treatment of endometriosis: a randomized, placebo-controlled, double-blind study. Lupron Study Group. Fertility and sterility (1990). pmid:2118858
  7. Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial. Human reproduction (Oxford, England) (2010). pmid:20089522
  8. Ulipristal acetate versus leuprolide acetate for uterine fibroids. The New England journal of medicine (2012). pmid:22296076
  9. Serum progesterone levels predict success of in vitro fertilization/embryo transfer in patients stimulated with leuprolide acetate and human menopausal gonadotropins. The Journal of clinical endocrinology and metabolism (1991). pmid:1909704
  10. Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation. Fertility and sterility (2001). pmid:11163814
  11. A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid. Chemical & pharmaceutical bulletin (1988). pmid:3136939
  12. One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate. Advanced drug delivery reviews (1997). pmid:10837564
  13. Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy. Nature medicine (2003). pmid:12754502

On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.

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