Research records indexed for Semax
This page carries 12 of the 207 records that the literature query returned for Semax, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 195 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is Semax.
Indexed records
| Record | Year | Study type | Model | n as stated | What it reported |
|---|---|---|---|---|---|
| Antidepressant-like and antistress effects of the ACTH(4-10) synthetic analogs Semax and Melanotan II on male rats in a model of chronic unpredictable stress pmid:39442746 | 2024 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Hippocampus; Rats, Sprague-Dawley; Disease Models, Animal; Chronic Disease; Peptides, Cyclic. |
| Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models pmid:35080861 | 2022 | research-article | other | Not stated | Indexed as research-article. study model from MeSH "Humans" with no interventional publication type. subject headings: Alzheimer Disease; Copper; Peptide Fragments; Membranes, Artificial; Adrenocorticotropic Hormone. |
| Brain Protein Expression Profile Confirms the Protective Effect of the ACTH<sub>(4-7)</sub>PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia-Reperfusion pmid:34201112 | 2021 | research-article | rodent | Not stated | Indexed as research-article. study model from MeSH "Rats". subject headings: Brain; Rats, Wistar; Brain Ischemia; Reperfusion Injury; Disease Models, Animal. |
| [The Peptide Drug ACTH(4-7)PGP (Semax) Suppresses mRNA Transcripts Encoding Proinflammatory Mediators Induced by Reversible Ischemia of the Rat Brain] pmid:34097675 | 2021 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Brain; Rats, Wistar; Brain Ischemia; Ischemia; Peptide Fragments. |
| Novel Insights into the Protective Properties of ACTH<sub>(4-7)</sub>PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats pmid:32580520 | 2020 | Research Support, Non-U.S. Gov't, research-article | rodent | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Rats". subject headings: Brain; Brain Ischemia; Infarction, Middle Cerebral Artery; Reperfusion Injury; Disease Models, Animal. |
| Composition of Colon Microbiota in Rats Treated with ACTH(4-7)-PGP Peptide (Semax) under Conditions of Restraint Stress pmid:32737723 | 2020 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Colon; Rats, Wistar; Disease Models, Animal; Peptide Fragments; Restraint, Physical. |
| Functional Connectomic Approach to Studying Selank and Semax Effects pmid:32342318 | 2020 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Brain; Amygdala; Prefrontal Cortex; Oligopeptides; Peptide Fragments. |
| Experimental Substantiation of Application of Semax as a Modulator of Immune Reaction on the Model of "Social" Stress pmid:31028579 | 2019 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Animals" with no rodent species heading. subject headings: Neutrophils; Animals, Outbred Strains; Hypersensitivity, Delayed; Peptide Fragments; Neuroprotective Agents. |
| [The efficacy of semax in the tretament of patients at different stages of ischemic stroke] pmid:29798983 | 2018 | Clinical Trial | human trial | Not stated | Indexed as clinical trial. study model from MeSH "Humans" with publication type "clinical trial". subject headings: Brain Ischemia; Brain-Derived Neurotrophic Factor; Peptide Fragments; Adrenocorticotropic Hormone; Stroke. |
| Effects of Semax on the Default Mode Network of the Brain pmid:30225715 | 2018 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Prefrontal Cortex; Nerve Net; Peptide Fragments; Nootropic Agents; Magnetic Resonance Imaging. |
| Modulation of GABA- and Glycine-Activated Ionic Currents with Semax in Isolated Cerebral Neurons pmid:29577196 | 2018 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Cerebellum; Hippocampus; Neurons; Cells, Cultured; Gamma-Aminobutyric Acid. |
| Semax, an analog of ACTH<sub>(4-7)</sub>, regulates expression of immune response genes during ischemic brain injury in rats pmid:28255762 | 2017 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Middle Cerebral Artery; Rats, Wistar; Brain Ischemia; Disease Models, Animal; Proline. |
Where this page sits
Compound page: Semax. Class: Neuroactive peptides.
Retrieved 2026-10-10.
Sources
- PubChem Compound Summary for CID 9811102, ACTH (4-7), Pro-Gly-Pro-. PubChem, National Library of Medicine (2026). pubchem:9811102
- Drugs@FDA application register query for this compound, no application records returned. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:semax
- Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain research (2006). pmid:16996037
- Rapid induction of neurotrophin mRNAs in rat glial cell cultures by Semax, an adrenocorticotropic hormone analog. Neuroscience letters (2001). pmid:11457573
- Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia. Cellular and molecular neurobiology (2010). pmid:19633950
- The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis. BMC genomics (2014). pmid:24661604
- Novel Insights into the Protective Properties of ACTH<sub>(4-7)</sub>PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats. Genes (2020). pmid:32580520
- [A nootropic adrenocorticotropin analog 4-10-semax (l5 years experience in its design and study)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova (1997). pmid:9173745
On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.