Research records indexed for Noopept
This page carries 12 of the 86 records that the literature query returned for Noopept, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 74 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is Noopept.
Indexed records
| Record | Year | Study type | Model | n as stated | What it reported |
|---|---|---|---|---|---|
| Physicochemical and structural analysis of N-phenylacetyl-L-prolylglycine ethyl ester (Noopept) - An active pharmaceutical ingredient with nootropic activity pmid:39298839 | 2025 | Journal Article | other | Not stated | Indexed as journal article. study model from assigned MeSH headings do not state a study model. subject headings: Dipeptides; Nootropic Agents; X-Ray Diffraction; Magnetic Resonance Spectroscopy; Molecular Structure. |
| Effects of noopept on ocular, pancreatic and renal histopathology in streptozotocin induced prepubertal diabetic rats pmid:36946173 | 2023 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Pancreas; Kidney; Diabetes Mellitus, Experimental; Streptozocin; Insulin. |
| Intranasal Administration of Forskolin and Noopept Reverses Parkinsonian Pathology in PINK1 Knockout Rats pmid:36614135 | 2022 | research-article | rodent | Not stated | Indexed as research-article. study model from MeSH "Rats". subject headings: Brain; Parkinson Disease; Protein Kinases; Dipeptides; Administration, Intranasal. |
| Effect of nootropic dipeptide noopept on CA1 pyramidal neurons involves α7AChRs on interneurons in hippocampal slices from rat pmid:36195298 | 2022 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Hippocampus; Pyramidal Cells; Interneurons; Rats, Sprague-Dawley; Proline. |
| Noopept Attenuates Diabetes-Mediated Neuropathic Pain and Oxidative Hippocampal Neurotoxicity via Inhibition of TRPV1 Channel in Rats pmid:34241806 | 2021 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Hippocampus; Rats, Wistar; Neuralgia; Diabetes Mellitus, Experimental; Dipeptides. |
| QbD-driven development of dissolving microneedle patch loaded with ultradeformable liposomes encapsulated Noopept: Exploring a patient friendly, once-daily option to manage dementia pmid:34126240 | 2021 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Swine; Rats, Sprague-Dawley; Dementia; Dipeptides; Liposomes. |
| Cognitive Enhancer Noopept Activates Transcription Factor HIF-1 pmid:33119829 | 2020 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Cell Line, Tumor; Neuroblastoma; Dipeptides; Transcription Factors; Neuroprotective Agents. |
| Effects of noopept on cognitive functions and pubertal process in rats with diabetes pmid:31356906 | 2019 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Rats, Sprague-Dawley; Diabetes Mellitus, Experimental; Insulin Resistance; Insulin; Blood Glucose. |
| Neuroprotective Dipeptide Noopept Prevents DNA Damage in Mice with Modeled Prediabetes pmid:31776952 | 2019 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Mice, Inbred Balb C". subject headings: Liver; Kidney; Mice, Inbred BALB C; Diabetes Mellitus, Experimental; Prediabetic State. |
| Drug with Neuroprotective Properties Noopept Does Not Stimulate Cell Proliferation pmid:30788746 | 2019 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Cell Line, Tumor; Peptides; Dipeptides; Ki-67 Antigen; Neuroprotective Agents. |
| Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices pmid:29313229 | 2018 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Neurons; Animals, Newborn; Rats, Wistar; Calcium; Dipeptides. |
| [The influence of self-massage combined with drug Noopept on the professional performance of teachers older.] pmid:30877834 | 2018 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Dipeptides; Massage; Self Care; Professional Competence; School Teachers. |
Where this page sits
Compound page: Noopept. Class: Neuroactive peptides.
Retrieved 2026-10-12.
Sources
- PubChem Compound Summary for CID 180496, 1-(2-Phenylacetyl)-L-prolylglycine ethy ester. PubChem, National Library of Medicine (2026). pubchem:180496
- Drugs@FDA application register query for this compound, no application records returned. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:noopept
- The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer's disease model. Journal of psychopharmacology (Oxford, England) (2007). pmid:17092975
- The effects of piracetam and its novel peptide analogue GVS-111 on neuronal voltage-gated calcium and potassium channels. General pharmacology (1997). pmid:9195198
- The major metabolite of dipeptide piracetam analogue GVS-111 in rat brain and its similarity to endogenous neuropeptide cyclo-L-prolylglycine. European journal of drug metabolism and pharmacokinetics (1997). pmid:9358206
- Neuroprotective properties of nootropic dipeptide GVS-111 in in vitro oxygen-glucose deprivation, glutamate toxicity and oxidative stress. Bulletin of experimental biology and medicine (2000). pmid:11177296
- GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience (2003). pmid:12711349
- Memory restoring and neuroprotective effects of the proline-containing dipeptide, GVS-111, in a photochemical stroke model. Behavioural pharmacology (1999). pmid:10780261
- Noopept stimulates the expression of NGF and BDNF in rat hippocampus. Bulletin of experimental biology and medicine (2008). pmid:19240853
- Neuroprotective and nootropic drug noopept rescues α-synuclein amyloid cytotoxicity. Journal of molecular biology (2011). pmid:21986202
- Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. Journal of biomedical science (2014). pmid:25096780
- Noopept normalizes parameters of the incretin system in rats with experimental diabetes. Bulletin of experimental biology and medicine (2014). pmid:25065315
- Noopept Attenuates Diabetes-Mediated Neuropathic Pain and Oxidative Hippocampal Neurotoxicity via Inhibition of TRPV1 Channel in Rats. Molecular neurobiology (2021). pmid:34241806
On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.